SLAMF1 activates autophagy and therapy responses in patients with chronic lymphocytic leukemia
SLAMF1 (Signaling Lymphocytic Activation Molecule Family 1), aka CD150, is a cell surface molecule involved in cell-cell interactions and in signal transduction in cells of the hematopoietic system. A group of scientists working in the Immunogenetics Unit of the Human Genetics Foundation headed by Silvia Deaglio, identified SLAMF1 as a marker of favorable prognosis for patients with chronic lymphocytic leukemia, the most common form of adult leukemia. The paper recently published by Cinzia Bologna and colleagues in the Journal of Clinical Investigation shows that SLAMF1 expression is necessary for cellular homeostasis, by regulating CLL cell localization... more
September 22, 2015
Synapses need only few bits
Deep learning is possibly the most exciting branch of contemporary machine learning. Complex image analysis, speech recognition and self-driving cars are just a few popular examples of a multitude of new applications where machine learning, and deep learning in particular, more.
Applications close March 31

Senior Scientist position (1-year)
The Human Genetics Foundation is seeking a senior scientist to work on a project titled "Identification of novel mutations and gene deregulation in breast and colon tumors". The project consists of bioinformatics analysis from NGS data coming from Exome-seq , ChIP-seq, RNA-seq, DECAP-seq. The project is coordinated by Prof. Salvatore Oliviero ... more
June 12, 2015

The group of Genomic Variation published a paper
investigating the effects of cigarette smoke exposure on genomic DNA methylation in twins with discordant smoking habits...
February, 5 2015

A new paper from the Epigenetic Group
about the development of a new method to map at single base resolution the presence of 5-formylcytosine (5fC) and 5-carbxylcytosine (5caC) more