November 11, 2013
The newly appointed Director of the Human Genetics Foundation, Gianluca Severi, takes up his office today.
Assoc Prof Gianluca Severi is a senior genetic and molecular epidemiologist with a national and international reputation in the field of cancer epidemiology gained during almost twenty years. His main research interest is genetic epidemiology, and, more recently, epigenetic epidemiology, of cancer. Between 2008 and 2013 he was the Deputy Director of the Cancer Epidemiology Centre of the Cancer Council Victoria (CEC), a leading research centre in Australia. In this role he had various responsibilities for large-scale collaborative studies including case-control studies, family studies and prospective and retrospective cohort studies. Assoc Prof Severi is an independent scientist with a career total of more than 180 peer-reviewed papers and a personal H-index of 32. MORE
The growing rate of available data generated by Next-Generation sequencing isnot counterbalanced by efficient data analysis.
NGI is a platform for Next Generation Sequencing data analysis by the Epigenetics Unit of HuGeF provides to the scientific community. MORE
Paper by the Immunogenetics Unit appears on Leukemia
The paper "Functional impact of NOTCH1 mutations in chronic lymphocytic leukemia" appeared on Leukemia and the review "Multiple Metamorphoses Of CD38 MORE
A paper by the Epigenetics Unit appears on Cell
gonizes DNA Methy
lation at Bivalent Promoters and Favors DNA Methylation at Gene Bodies in ESCs
The de novo DNA methyltransferase 3-like (Dnmt3L) is a catalytically inactive DNA methyltransferase that cooperates with Dnmt3a and Dnmt3b to methylate DNA. Dnmt3L is highly expressed in mouse embryonic stem cells (ESCs), but its function in these cells is unknown MORE
Paper by Barbara Pardini et al. on Clinical Cancer Research
Variation within 3' UTRs of base excision repair genes and response to therapy in colorectal cancer patients: a potential modulation of microRNAs binding
Polymorphisms in the 3'UTR region could alter the microRNA binding, READ MORE